In the yeast Saccharomyces cerevisiae, the opposite effect is observed: under low zinc conditions, an elevated glutathione concentration is found. So right there, in the abstract, they say that mammals and yeast behave in an opposite fashion when it comes to zinc and glutathione
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The US FDA has issued warnings about intravenous glutathione for skin lightening, noting that the safety of IV administration for this purpose is unknown
Factors include condition-specific responses, patch material, cell type, individual health, and age